PROSPECTIVE COHORT CANNABIS USE STUDY OF, PREDISPOSITION FOR PSYCHOSIS, AND SYMPTOMS IN YOUNG PEOPLE.
OBJECTIVE: To investigate the relation between cannabis use and psychotic symptoms in individuals with above average predisposition to psychosis who first used cannabis
PARTICIPANTS: 2437 young people (aged 14 to 24 yrs) With and without predisposition for psychosis.
MAIN OUTCOME MEASURE: Psychotic symptoms at follow up as a function of cannabis use and predisposition for psychosis at base
RESULTS; After the adjustment of age, sex socio-economic status, urbanicity, childhood trauma, predisposition for psychosis as base line , and use of other drugs , Tobacco and alcohol. Cannabis used at base line level increased the cumulative incidence of psychotic symptoms at follow up 4 years later. The adjusted ratio 1,69 at 95%. Confidence interval 1,13 to 2,46. The effect of cannabis use was much stronger in those with any predisposition for psychosis at baseline (23,8%) Adjusted difference in risk 95%. At a confidence interval 7.9 to 39,7 P = 0,003 than those without (5,6 % The risk difference in the predisposition group was significantly greater than the risk difference in the non-predisposition group. There was a dose response relation with increasing frequency of cannabis use.
Predisposition for psychosis at baseline did not significantly predict cannabis use four years later. (Adjusted odd ratio 1,42.. 95%. Confidence interval 0,88 to 2,31
Conclusion: Cannabis used moderately increases the risk of psychotic symptoms in young people but has a much stronger effect in those with evidence of predisposition for psychosis
When ever opposition arises touching on the cannabis issue and proof is provided or not then still those that are pro-cannabis shout for a study. What has been reproduced above is a study and has been compiled and accepted by the medical fraternity.
I personally refuse to acknowledge any statement or theories from those that are not qualified to produce such theories. Sources: Google title AND/OR BRITANNICA ENCYCLOPAEDIA
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