They are also seeking to have Trade and Industry Minister Alec Erwin taken into custody on the same charge. In a "people's docket" handed to police, TAC said it demanded an investigation into the death of "many thousands of people who died from Aids or Aids-related illnesses and whose deaths could have been prevented had they been given access to treatment."
"We further demand that the accused be arrested and charged with the offence of culpable homicide or negligently causing the death of these people.
"We believe many thousands of people can bear witness to these horrible crimes."
TAC said that in their capacities as ministers both of them had the legal duty and power to prevent Aids-related deaths by developing a treatment and prevention plan and providing medicines.
Some of the TAC members at the police station held up large red "wanted" posters bearing the ministers' photographs. TAC is seeking to have a symbolic 600 people arrested in the next week in the disobedience campaign.
The organisation is seeking an "irreversible and unequivocal" government commitment to a public-sector antiretroviral (ARV) treatment programme for people with HIV/Aids.
The launch of the week-long campaign coincided with a government campaign in daily newspapers on Thursday to convince people it did have a treatment plan.
In large advertisements it says it is continuing to address "barriers" to the introduction of ARV therapy, including high drug prices and weaknesses in health infrastructure.
" class="elevenLink" title="TAC starts civil uproar at copshop" onClick="javascript: pageTracker._trackPageview('/outbound/relatedlink');">TAC starts civil uproar at copshop