Anti-depressants a risk for newborns

2012-01-14 17:54

Stockholm - Newborns of mothers on antidepressants are more likely to have dangerously high blood pressure in the lungs, according to a study published on Friday in the British Medical Journal.

Taking so-called selective serotonin reuptake inhibitors (SSRIs) - such as Prozac - after the 20th week of pregnancy more than doubled the risk, the study found.

SSRIs are a class of compounds typically used to treat depression, anxiety disorders, and some personality disorders.

The study, led by Helle Kieler at the Karolinska Institute's Centre for Pharmacoepidemiology in Stockholm, looked at 1.6 million single births between 1996 and 2007 in Denmark, Finland, Iceland, Norway and Sweden.

In the general population, the number of newborns with the condition is 1.2 in 1 000, with a mortality rate among babies with high blood pressure in the lungs of 15%.

Newborns of about 17 000 mothers who filled out prescriptions for SSRIs before the eighth week of pregnancy, showed a slight increased risk of having the condition.

But for 11 000 expectant mothers who took the drugs after week 20 of their pregnancies, the risk more than doubled.

Even for this group, however, the absolute risk for newborns remained fairly low: about three in 1 000 - or 0.2% -  the researchers said.

Kieler nonetheless suggested that doctors who treat depression in pregnant patients consider a non-drug approach to the condition.

"As the risk in association with treatment in late pregnancy seems to be more than doubled, we recommend caution when treating pregnant women with SSRIs," the researchers concluded.

The drugs analysed included fluoxetine, citalopram, paroxetine, sertraline, fluvoxamine and escitalopram. Fluoxetine is better known under the brand name Prozac.

Read more on:    research

Join the conversation!

24.com encourages commentary submitted via MyNews24. Contributions of 200 words or more will be considered for publication.

We reserve editorial discretion to decide what will be published.
Read our comments policy for guidelines on contributions.
NEXT ON NEWS24X

linking and moving

2015-04-22 07:36

24.com publishes all comments posted on articles provided that they adhere to our Comments Policy. Should you wish to report a comment for editorial review, please do so by clicking the 'Report Comment' button to the right of each comment.

Comment on this story
0 comments
Comments have been closed for this article.

Inside News24

 
/News

Book flights

Compare, Book, Fly

Traffic Alerts
There are new stories on the homepage. Click here to see them.
 
English
Afrikaans
isiZulu

Hello 

Create Profile

Creating your profile will enable you to submit photos and stories to get published on News24.


Please provide a username for your profile page:

This username must be unique, cannot be edited and will be used in the URL to your profile page across the entire 24.com network.

Settings

Location Settings

News24 allows you to edit the display of certain components based on a location. If you wish to personalise the page based on your preferences, please select a location for each component and click "Submit" in order for the changes to take affect.




Facebook Sign-In

Hi News addict,

Join the News24 Community to be involved in breaking the news.

Log in with Facebook to comment and personalise news, weather and listings.