Aspirin reduces cancer in high-risk patients

2011-10-28 10:29

kalahari.com

London - People with a genetic condition that puts them at increased risk of colon cancer may lower their chance of developing the disease by taking daily aspirin, a study suggests.

The finding, however, doesn't apply to the general public, since aspirin can have side effects such as gastrointestinal bleeding.

The 861 people in the British study had Lynch syndrome, a rare, inherited disorder that puts them at high risk for cancers including those of the colon. The condition accounts for about 3% to 5% of colon cancer cases.

Previous research had suggested that aspirin could help prevent colon cancer in that group.

In the latest study, people were assigned to take 600mg of aspirin daily - about two regular strength aspirin - or dummy pills. After more than four years of follow-up, the study didn't find a significant difference in how many people in each group developed their first colon cancer.

Side effects

But they did see one when they looked at long-term participants who regularly took their pills for at least two years. Among the 258 people on aspirin, there were 10 colon cancer cases. That compares to 23 cases in the 250 people on dummy pills. Rates of side effects like bleeding and ulcers in the stomach were similar in both groups.

"This is good news for a very specific population," said Asad Umar, a cancer prevention expert at the US National Cancer Institute who was not linked to the study. He said the finding could apply to about 15% of colon cancer patients who have genetic defects similar to Lynch syndrome.

But Umar warned aspirin should only be recommended for people at high risk for colon cancer.

"We're not ready to say aspirin is useful for the general public," he said. "There are still a lot of toxicity concerns."

The paper was published on Friday in the journal Lancet. It was paid for by groups including the EU, Cancer Research UK, Bayer Corporation, the original maker of aspirin, and others.

Newcastle University's Dr John Burn, the study's chief investigator, reported receiving a speaker's fee from Bayer in 2010.
- AP
Read more on:    cancer  |  research
NEXT ON NEWS24X
SHARE:

Read News24’s Comments Policy

24.com publishes all comments posted on articles provided that they adhere to our Comments Policy. Should you wish to report a comment for editorial review, please do so by clicking the 'Report Comment' button to the right of each comment.

Comment on this story
0 comments
Add your comment
Comment 0 characters remaining
 

Inside News24

 
/News

Jobs in Cape Town [change area]

Jobs in Western Cape region

Junior Bookkeeper - Motor Industry (CT – Southern Suburbs)

Cape Town Southern Suburbs
West Coast Personnel
R8 000 - R10 000 Per Month

PR Account Manager

Cape Town CBD
Switch Consultants (Pty) Ltd
R15 000 - R18 000 Per Month

C # Developer ( Hire Resolve )

Cape Town
Hire Resolve
R15 000 - R18 000 Per Month

Property [change area]

Travel - Look, Book, Go!

Magical Massinga

Spend 5 nights at the gorgeous Massinga Beach Lodge in Mozambique and only pay for 4 from R13 220 per person sharing. Includes return flights, accommodation, transfers and romantic turndown. Book now!

Kalahari.com - shop online today

20% off all TV Series!

Want to have a chilled day at home? Get 20% off TV series, the perfect excuse to "veg out". Shop now!

Save R700 on the Hisense LED TV Now R2499

Get the Hisense 32” HD ready LED TV for only R2499. Offer valid while stocks last. Shop now!

Up to 40% off fashion accessories

Save up to 40% on selected handbags, purses, watches, jewellery and more. Offer valid while stocks last. Shop now!

Save up to R2000 on top electronics

Get every day mind bowing savings on top electronics. Offer valid while stocks last. Shop now!

As seen on TV - New book releases at only R199 each

Get mind blowing book savings on new titles. Offer valid while stocks last. Shop now!

OLX Free Classifieds [change area]

Samsung Galaxy s4

Mobile, Cell Phones in South Africa, Western Cape, Cape Town. Date October 24

Best bargain in big bay

Real Estate, Houses - Apartments for Sale in South Africa, Western Cape, Cape Town. Date October 25

VW Golf 6, 1.6 Trendline (Excellent condition)

Vehicles, Cars in South Africa, Western Cape, Cape Town. Date October 25

Horoscopes
Aquarius
Aquarius

Your ideas may feel like a sea of thoughts swimming around every which way, and now you need to find something to contain them in...read more

There are new stories on the homepage. Click here to see them.
 
English
Afrikaans
isiZulu

Hello 

Create Profile

Creating your profile will enable you to submit photos and stories to get published on News24.


Please provide a username for your profile page:

This username must be unique, cannot be edited and will be used in the URL to your profile page across the entire 24.com network.

Settings

Location Settings

News24 allows you to edit the display of certain components based on a location. If you wish to personalise the page based on your preferences, please select a location for each component and click "Submit" in order for the changes to take affect.








Facebook Sign-In

Hi News addict,

Join the News24 Community to be involved in breaking the news.

Log in with Facebook to comment and personalise news, weather and listings.