Microchip delivers bone-loss drug

2012-02-16 22:03

Vancouver  - A microchip inserted under the skin has been shown for the first time to successfully deliver a bone-loss drug to a small sample of women, according to US-led research published on Thursday.

The device may someday allow patients to avoid daily injections of medication and permit doctors to adjust their doses from afar, said the study which appears in the journal Science Translational Medicine.

The technology "gives physicians a real-time connection to their patient's health, and patients are freed from the daily reminder, or burden, of disease," said co-author Robert Langer, a professor of cancer research at the Massachusetts Institute of Technology.

Langer and colleagues were to present their findings later on Thursday at the annual meeting of the American Association for the Advancement of Science in Vancouver, Canada.

The device is about the size of a pacemaker and contains daily doses of medication inside small wells that open up either on a predetermined schedule, or when the chip is given a wireless signal to release the drugs.

"Each of these wells is covered by a nano-thin layer of gold which protects the drug for years if needed and prevents it from being released," said Langer in a statement released ahead of the presentation.

The wireless signal causes the gold to dissolve and allows the drug to enter the bloodstream.

Raised concerns

In this case, researchers tested the device on seven women age 65-70 in Denmark who were prescribed the drug teriparatide for osteoporosis. The microchip was implanted just below their waistlines.

After tracking the women for 12 months, researchers found that the treatment improved bone formation and reduced the risk of bone fracture, and delivered the drug just as effectively as daily injections.

However, the same issues that raised concerns in animal studies were also observed in the women: the formation of fibrous collagen-based tissue around the microchip.

The presence of the tissue has raised concerns among researchers over its potential to interrupt drug delivery, though no such problems were observed in the one-year study, after which the women had the chips removed.

Scientists plan to continue studies on the microchip delivery system in heart disease, multiple sclerosis, cancer and chronic pain. The device is likely about five years away from potential market approval, the authors said.

Read more on:    canada  |  denmark  |  health  |  research
NEXT ON NEWS24X

Read News24’s Comments Policy

24.com publishes all comments posted on articles provided that they adhere to our Comments Policy. Should you wish to report a comment for editorial review, please do so by clicking the 'Report Comment' button to the right of each comment.

Comment on this story
1 comment
Add your comment
Comment 0 characters remaining
 

Inside News24

 
 

DA ad scores nearly half a millions hits on YouTube

The DA's "Ayisafani" (It's not the same) election TV advert - originally pulled off the air by the SABC - has garnered nearly half a million views on YouTube.

 
 

Latest elections multimedia

Why Jack Parow wants you to vote on 7 May
The ad the SABC doesn't want to air
Elections 2014 in one cartoon
This year's election posters
 
Traffic
Lottery
 
  • Saturday Newlands - 12:32 PM
    Road name: M3 Inbound
    DELAYS between Wynberg Hill and UCT due to 2 Oceans Marathon
  • Thursday Sir Lowry's Pass - 05:35 AM
    Road name: Old Sir Lowrys Pass Road
    TRAFFIC LIGHTS not working at Bezweni Road
 
More traffic reports...
 

Jobs in Cape Town [change area]

Property [change area]

Travel - Look, Book, Go!

Escape winter, head to Mauritius

Escape winter by spending 7 nights in Mauritius' tropical bliss from R13 215 per person sharing. Includes return flights, airport transfers and accommodation. Book now!

Kalahari.com - shop online today

Get many eggs in one basket!

Gaming bundles: 2 Super Hits games for R99, 3 Disney games for R99 and more + exclusive accessory bundles only available on kalahari.com. While stocks last. Shop now!

25% off bestselling books!

The Real Meal Revolution by Tim Noakes, Jeffrey Archer’s Be Careful What You Wish for, Man’s Search for Meaning by Victor E. Frank and many more titles. Shop now!

Up to 25% off electronics

Buy top electronics and save up to 25%. Such as kalahari.com’s 1# selling product the gobii eReader, Patriot X Porter flash drive, Asus Nexus 7” 3G tablet, Samsung Galaxy SIII, Lenovo G580 Notebook and many more. Shop now!

DStv HD PVR Decoder now R949

The DStv HD PVR Decoder has further revolutionised the television experience with lifelike viewing, sharper images, more vibrant colours and precision picture quality. Now R949, save R550. Offer valid while stocks last. Shop now!

Up to 30% off appliances & homeware

Save up to 30% on appliances and homeware this Easter! Offer valid while stocks last. Shop now.

OLX Free Classifieds [change area]

Samsung Galaxy s4

Mobile, Cell Phones in South Africa, Western Cape, Cape Town. Date October 24

Best bargain in big bay

Real Estate, Houses - Apartments for Sale in South Africa, Western Cape, Cape Town. Date October 25

VW Golf 6, 1.6 Trendline (Excellent condition)

Vehicles, Cars in South Africa, Western Cape, Cape Town. Date October 25

BlackBerry Curve 8520

Wi-Fi enabled With the BlackBerry Curve 8520 connect to your home...

From R1100.00

I'm shopping for:

Horoscopes
Aquarius
Aquarius

Self-indulgence may be strong today. You may want to enjoy yourself to the fullest and share it with those that make you feel...read more

There are new stories on the homepage. Click here to see them.
 
English
Afrikaans
isiZulu

Hello 

Create Profile

Creating your profile will enable you to submit photos and stories to get published on News24.


Please provide a username for your profile page:

This username must be unique, cannot be edited and will be used in the URL to your profile page across the entire 24.com network.

Settings

Location Settings

News24 allows you to edit the display of certain components based on a location. If you wish to personalise the page based on your preferences, please select a location for each component and click "Submit" in order for the changes to take affect.








Facebook Sign-In

Hi News addict,

Join the News24 Community to be involved in breaking the news.

Log in with Facebook to comment and personalise news, weather and listings.