The third film in the vampire franchise based on the books by Stephenie Meyer is up for awards including Best Movie, Best Female Performance, Best Villain, Best Jaw-Dropping Moment, Best Fight and Best Kiss while co-stars Robert Pattinson and Taylor Lautner will compete in the Best Male Performance category.
Inception starring Leonardo DiCaprio follows closely behind with seven nominations, Harry Potter and the Deathly Hallows: Part 1, The Social Network and Black Swan have six, five and four nods respectively in the awards voted for by the public.
A new category - best line from a movie - has been added to the show this year, with Grown Ups, Easy A, The Social Network and Inception all in contention.
This year's ceremony will be hosted by Saturday Night Live star Jason Sudeikis and will air live on Sunday June 5, from the Gibson Amphitheatre in Universal City, California.
Voting for the 2011 MTV Movie Awards is now open at MTV.com and will close on Saturday June 4. The Best Movie category will remain open for voting throughout the live show.
The 2011 MTV Movie Awards Nominations are:
Harry Potter and the Deathly Hallows, Part 1
The Social Network
The Twilight Saga: Eclipse
Best Female Performance
Emma Stone - Easy A
Emma Watson - Harry Potter and the Deathly Hallows, Part 1
Jennifer Aniston - Just Go With It
Kristen Stewart - The Twilight Saga: Eclipse
Natalie Portman - Black Swan
Best Male Performance
Daniel Radcliffe - Harry Potter and the Deathly Hallows, Part 1
Jesse Eisenberg - The Social Network
Robert Pattinson - The Twilight Saga: Eclipse
Taylor Lautner - The Twilight Saga: Eclipse
Zac Efron - Charlie St. Cloud
Best Breakout Star
Andrew Garfield - The Social Network
Chloe Grace Moretz - Kick-Ass
Hailee Steinfeld - True Grit
Jay Chou - The Green Hornet
Olivia Wilde - TRON: Legacy
Xavier Samuel - The Twilight Saga: Eclipse
Best Comedic Performance
Adam Sandler - Just Go With It
Ashton Kutcher - No Strings Attached
Emma Stone - Easy A
Russell Brand - Get Him to the Greek
Zach Galifianakis - Due Date
Best Line From A Movie (New Category)
Alexys Nycole Sanchez, Grown Ups: "I want to get chocolate wasted."
Amanda Bynes and Emma Stone, Easy A: Amanda Bynes: "There is a higher power that will judge you for your indecency." Emma Stone: "Tom Cruise?"
Jesse Eisenberg, The Social Network: "If you guys were the inventors of Facebook, you'd have invented Facebook."
Justin Timberlake and Andrew Garfield, The Social Network: Justin Timberlake: "... A million dollars isn't cool. You know what's cool?" Andrew Garfield: "A billion dollars. And that shut everybody up."
Tom Hardy, Inception: "You mustn't be afraid to dream a little bigger darling."
Christoph Waltz - The Green Hornet
Leighton Meester - The Roommate
Mickey Rourke - Iron Man 2
Ned Beatty - Toy Story 3
Tom Felton - Harry Potter and the Deathly Hallows, Part 1
Amy Adams vs. The Sisters - The Fighter
Chloë Grace Moretz vs. Mark Strong - Kick-Ass
Daniel Radcliffe, Emma Watson and Rupert Grint vs. Death Eaters - Harry Potter and the Deathly Hallows, Part 1
Joseph Gordon-Levitt vs. Hallway Attacker - Inception
Robert Pattinson vs. Bryce Dallas Howard and Xavier Samuel - The Twilight Saga: Eclipse
Ellen Page and Joseph Gordon-Levitt - Inception
Emma Watson and Daniel Radcliffe - Harry Potter and the Deathly Hallows, Part 1
Kristen Stewart and Robert Pattinson - The Twilight Saga: Eclipse
Kristen Stewart and Taylor Lautner - The Twilight Saga: Eclipse
Natalie Portman and Mila Kunis - Black Swan
Best Jaw-Dropping Moment
James Franco, 127 Hours - Cuts Off His Arm
Justin Bieber, Justin Bieber: Never Say Never - Performance Spectacular
Leonardo DiCaprio and Ellen Page, Inception - Paris Café Scene
Natalie Portman, Black Swan - Mutilation: Pulls the Skin off Her Finger
Steve-O, Jackass 3D - Port-A-Potty Bungee Stunt
Best Scared-As-Shit Performance
Ashley Bell - The Last Exorcism
Ellen Page - Inception
Jessica Szohr - Piranha 3D
Minka Kelly - The Roommate
Ryan Reynolds – Buried
Biggest Badass Star
Alex Pettyfer - I Am Number Four
Chloë Grace Moretz - Kick-Ass
Jaden Smith - The Karate Kid
Joseph Gordon-Levitt - Inception
Robert Downey Jr - Iron Man 2