"Two men were critically injured in a helicopter crash in an abandoned industrial park off 16th Avenue in Midrand this afternoon," said Netcare911 spokesperson Jeffrey Wicks.
"Common cause information suggests that the helicopter crashed and the wreckage disintegrated, the largest segment coming to rest against concrete palisade fencing.
"Netcare911 paramedics arrived at the scene to find two occupants in a critical condition and they immediately initiated treatment," Wicks said.
"One man was airlifted by helicopter to the Netcare Sunninghill Hospital. The other man was taken by ambulance to the same medical facility," he said.
The scene of the crash is at the junction of 16th Road and 2nd Avenue near the N1 highway.
"The cause of the accident and the series of events leading up to it remain uncertain and will form the subject of a Civil Aviation Authority investigation," he said.