Visibly tired by 15-hour days, frenetic flying and driving round the country to address tens of thousands in a campaign dominated by threats and fear of attack, the cricket legend is nothing if not focused.
"This is a revolution taking place," he told AFP after a couple of days of hard campaigning in Punjab, his home province and the political backbone of Pakistan which elects a little over half the seats in the national assembly.
"When I came to politics 17 years ago, I had already conquered my fear of dying because I knew I was going to challenge the status quo," the 60-year-old said. But security is clearly a major preoccupation.
Khan says he's on the "top five hit list". He may not use the bulletproof glass screens used by other politicians at public rallies, but he travels in an armoured car with an armed police escort.
A rally in Karachi, Pakistan's largest city, was cancelled on Sunday after attacks on rival parties killed more than 20 people. Attacks targeting the election campaign have so far killed nearly 60 people ahead of the 11 May polls.
"We couldn't take a risk. It's just too dangerous. I mean you can't risk the life of other people," the 60-year-old said.
No bullet proof
Khan has two sons by his ex-wife Jemima Khan, daughter of the late billionaire tycoon James Goldsmith, but they live in Britain and he has not seen them for several months.
"My older son worries. You know he worries, obviously, because when he hears what's going on in Pakistan," he says.
Khan and Nawaz Sharif, the two-time prime minister whose PML-N party is tipped to win, are the only two leaders addressing big rallies.
The three main parties in the outgoing government, the PPP, the MQM and the ANP, have curtailed public gatherings in the face of direct Taliban threats.
Khan's campaign is about mobilising the masses, exploiting disaffection with a corrupt elite, tapping into anti-American sentiment that blames many of the countries woes on the United States and promising to fix a crippling power crisis.
"If my politics is different... I can't be standing behind a bullet-proof screen and connecting with the people," he said.
When he bounded up to the microphone in Sarghoda, a university and garrison town in the Punjab farm belt, he deliberately stepped in front, not behind the protective screen party workers had hauled onto the podium.
To his supporters he is the hero who led Pakistan's cricket team to World Cup victory in 1992 and then set up the best cancer hospital in the country.
He went into politics in 1996, founding his Pakistan Tehreek-e-Insaaf (Movement for Justice) party determined to break the stranglehold of dynastic politics.
But only in October 2011, when he attracted a crowd of more than 100 000 - mostly young people, women and middle class voters - in his home town of Lahore, did he emerge from celebrity lightweight into serious contender.
He claims to be leading a "tsunami" of change, promising to improve governance and education, solve the energy crisis and balance the books by introducing tax reform and slashing expenditure.
His core base is the emerging middle class, which is socially conservative. But to alarmed detractors he is "Taliban Khan" - soft on Islamist militants and naive in his criticism of the US war on al-Qaeda and the Taliban.
Sympathy for Musharraf
He opposes US drone strikes and calls for peace talks with the Taliban, which the government blames for killing 30 000 people over the last decade.
Although Khan believes he will be Pakistan's next prime minister, analysts say he is more likely to secure 10-30 seats in the 342-member national assembly - a breakthrough that could make him kingmaker of an incoming coalition.
But he refuses to share power with the PPP, which led the national government for the last five years, or PML-N, which has ruled Punjab, saying that his party will go into opposition if they do not win.
Scathing about Sharif and President Asif Ali Zardari, he does, however, have words of pity for former military ruler Pervez Musharraf, who returned home last month from self-imposed exile only to be put under house arrest.
"He sent me a message once saying if he and I got together, then 95% of Pakistan was with us. I mean that would have been a suicide attack on my party," he said.
"Anyway, it's something I have always had for underdogs, I feel sorry for him, although he did a lot of damage to Pakistan."