An aspirin a day can keep cancer at bay - study

2012-03-21 22:11

London - Three new studies published on Wednesday added to growing scientific evidence suggesting that taking a daily dose of aspirin can help prevent, and possibly treat, cancer.

Previous studies have found that daily aspirin reduces the long-term risk of death due to cancer, but until now, the shorter-term effects have been less certain - as has the medicine's potential in patients already diagnosed with cancer.

The new studies, led by Peter Rothwell of Britain's Oxford University, found that aspirin also has a short-term benefit in preventing cancer, and that it reduces the likelihood that cancers will spread to other organs by about 40 to 50%.

"These findings add to the case for use of aspirin to prevent cancer, particularly if people are at increased risk," Rothwell said.


"Perhaps more importantly, they also raise the distinct possibility that aspirin will be effective as an additional treatment for cancer - to prevent distant spread of the disease."

This was particularly important because it is the process of spread of cancer, or "metastasis", which most often kills people with the disease, he added.

Aspirin, originally developed by Bayer, is a cheap over-the-counter drug generally used to combat pain or reduce fever.

The drug reduces the risk of clots forming in blood vessels and can therefore protect against heart attacks and strokes, so it is often prescribed for people who already suffer with heart disease and have already had one or several attacks.

Aspirin also increases the risk of bleeding in the stomach to about one patient in every thousand per year, a factor which has fuelled an intense debate about whether doctors should advise patients to take it as regularly as every day.

Deeper research

Last year, a study by British researchers questioned the wisdom of daily aspirin for reducing the risk of early death from a heart attack or stroke because they said the increased risk of internal bleeding outweighed the potential benefit.

Other studies, including some by Rothwell in 2007, 2010 and 2011, found that an aspirin a day, even at a low dose of about 75mg, reduces the long-term risk of developing some cancers, particularly bowel and oesophageal cancer, but the effects don't show until eight to 10 years after the start of treatment.

Rothwell, whose new studies were published in The Lancet and The Lancet Oncology journals on Wednesday, said this delay was because aspirin was preventing the very early development of cancers and there was a long time lag between this stage and a patient having clinical signs or symptoms of cancer.

Rothwell and others said deeper research was now needed into aspirin as a potential treatment for cancer in patients whose disease has not yet spread.

"No drug has been shown before to prevent distant metastasis and so these findings should focus future research on this crucial aspect of treatment," he said.

Peter Johnson, chief clinician at the charity Cancer Research UK, said his group was already investigating the anti-cancer properties of aspirin. "These findings show we're on the right track," he said.

In a written commentary on the research in The Lancet, Andrew Chan and Nancy Cook of Harvard Medical School in the United States said it was "impressive" and moved health experts "another step closer to broadening recommendations for aspirin use".

  • Hugh_Influence - 2012-03-21 22:30

    What a load of drivel. Go peddle your drugs somewhere else man.

      Poaul Zwarts - 2012-03-22 07:26

      Aspirin is so cheap and made by so many companies, that no-one in particular will benefit from 'peddling' it to you. This is pure research...

      Hugh_Influence - 2012-03-22 12:04

      Yeah except for the part where billions of people swallow them every day so the companies make a fortune, and the fact that it can eat a hole through your stomach. Also, thin blood isn't great when you're in an accident is it.

  • Lauden Kirk - 2012-03-22 06:58

    Bicarbonate soda cancer cure: google

  • raath - 2012-03-22 07:05

    If you are thinking about starting on aspirin... before you reach for the aspirin, please discuss this with your doctor first!

      Hugh_Influence - 2012-03-22 12:05

      I don't think anyone should be popping pills on a daily basis unless there's a VERY good reason for it. Pharmaceutical companies love to instill fear for bucks.

      raath - 2012-03-22 14:00


  • jacques.buckle - 2012-03-22 12:54

    aspirin wont be good for me.

  • johannes.buckle - 2012-03-22 13:37

    Have been popping for the past 15 years since having a light stroke. If in an accident as Hugh says tough - thin blood will flow so try to prevent! Neurosurgeon at the time said all South African men over the age of 35 not taking must have their heads read - VERY prone to heart attacks and strokes.

      raath - 2012-03-22 13:58

      It affects blood clotting (it doesn't really "thin" the blood - that is a misconception) - I used 70mg a day (about a quarter Disprin) and I suffered inexplicable nose bleeds. Not everyone needs a daily dose of aspirin.

  • Getafix - 2012-03-22 13:49

    Hemp Oil cures Cancer.

  • tyrese.cousintony - 2013-02-20 00:55

    I am so grateful to Doctor Melamede for saving my life with his Hemp Oil Medical service. I give thanks to God almighty for having the opportunity to meet him and i am so happy that i am no more a cancer patient anymore. Thank you so much Doctor Melamede for helping to save my life. For all those who have issue with Cancer should take the problem to Doctor Melamede and see it solved for life. contact:

  • pages:
  • 1