GM mosquitoes released to fight dengue

2011-01-26 16:08

Kuala Lumpur - Malaysia released about 6 000 genetically modified mosquitoes into a forest in the first experiment of its kind in Asia aimed at curbing dengue fever, officials said.

The field test is meant to pave the way for the official use of genetically engineered Aedes aegypti male mosquitoes to mate with females and produce offspring with shorter lives, thus curtailing the mosquito population. Only female Aedes aegypti mosquitoes spread dengue fever, which killed 134 people in Malaysia in 2010.

A similar trial in the Cayman Islands last year, the first of its kind, resulted in a dramatic drop in the mosquito population in a small area studied by researchers.

The plan has sparked criticism by some Malaysian environmentalists, who fear it might have unforeseen consequences, such as the inadvertent creation of uncontrollable mutated mosquitoes. Critics also say such plans could leave a vacuum in the ecosystem that is then filled by another insect species, potentially introducing new diseases.

Government authorities have tried to allay the concerns by saying they are conducting small-scale research and will not rush into any widespread release of mosquitoes.


The Malaysian government-run Institute for Medical Research said it released about 6 000 non-biting sterile male lab mosquitoes in an uninhabited forest area in eastern Malaysia on December 21. Another 6 000 wild male Aedes aegypti mosquitoes were also placed in the area for scientific comparison, it said in a statement.

The institute provided few details of the experiment, but said it was "successfully" concluded on January 5, and that all the mosquitoes were killed with insecticide. It was not planning to release any more mosquitoes until the analysis of the results of the lab mosquitoes' life span and extent of their dispersal in the wild is complete.

It was the first such trial in Asia, an official in the Ministry of Natural Resources and Environment said on condition of anonymity because he was not authorised to make public statements.

In the Cayman Islands, genetically altered sterile male mosquitoes were also set loose by scientists in a 16ha region between May and October last year. By August, mosquito numbers in that area dropped by 80% compared with a neighbouring area where no sterile mosquitoes were released.

The scientists' modeling estimates suggested an 80% reduction in mosquitoes should result in fewer dengue infections.

Malaysian Prime Minister Najib Razak said last year the project was an "innovative" way to fight dengue after a lack of success in campaigns urging Malaysians to keep neighbourhoods free of stagnant water where mosquitoes can breed.

The number of dengue-linked deaths in Malaysia increased 52% last year from 88 deaths in 2009. The total dengue infections rose 11% from 2009 to more than 46 000 cases last year.

Dengue fever is common in Asia and Latin America. Symptoms include high fever, joint pains and nausea, but in severe cases, it can lead to internal bleeding, circulatory shutdown and death. There is no known cure or vaccine.

  • - 2011-01-26 16:31

    Don't mess with nature! Something else will start because of this that nobody has thought of.

      wesleywt - 2011-01-26 16:34

      So don't do ANYTHING. Stay right where you are. Something might happen. Can you see how ridiculous this sounds?

  • wesleywt - 2011-01-26 16:36

    So don't do ANYTHING. Stay right where you are. Something might happen. Can you see how ridiculous this sounds?

  • Peter - 2011-01-27 07:25

    I agree with CharVal, don't mess with nature! GM foods has already been discovered to be a global disaster (i.e., mice fed solely on GMOs are born sterile by the third generation). Wonder what this tampering with nature is yet to reveal to us? When will mankind learn to stop playing God?

      Spookhuis - 2011-01-27 08:13

      Maybe it's not such a bad thing as the worlds population explodes to over 6 billion

  • D-Man - 2011-01-27 09:00

    We already have poorly covered up problems from messing with rBGH. Where is this going to stop?

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