(WARNING: This video contains spoilers)
Over the show's 16 seasons Grey's Anatomy had its fair share of drama that has left fans reeling.
In this video, MsMojo takes a look at incidents from this medical drama that took place when audiences least expected it, along with the fallout from these moments.
The countdown includes Meredith's near-death experience, Jackson objects to April's wedding, Seattle Grace explodes, and more!
READ MORE| 'Grey's Anatomy' season 16 to end early
Compiled by Leandra Engelbrecht