Markets retreated in Asia on Tuesday as uncertainty over the China-US trade talks was compounded by increasing tensions in Hong Kong and an economic crisis in Argentina.
Investor confidence has been knocked this month by a perfect storm of negative issues, only slightly offset by hopes for further central bank easing measures as the global outlook dims.
Comments from Donald Trump throwing next month's planned trade talks into doubt, as well as his decision to unveil more tariffs on Chinese goods, sent equities tumbling last week and analysts at Goldman Sachs have said they do not expect a deal before the 2020 US presidential election.
The Wall Street titan also warned the standoff could hit US growth, while Treasury yields plunged in a sign of growing concerns for the country's economic health.
All three main indexes on Wall Street ended more than one percent lower on Monday, while there were also losses in Europe and gold - a go-to asset in times of turmoil - climbed back above $1 500 to sit around six-year highs.
Increasing unrest in Hong Kong was also moving into global investors' view, as protests extend into a third month, with the city's airport - a major world transport hub - cancelling all flights in and out on Monday evening as thousands of demonstrators descended.
The demonstrations are raising pressure on Chief Executive Carrie Lam and led Beijing to warn of "terrorism emerging".
Stephen Innes, managing partner at VM Markets, said: "Dropping the 'T' word is particularly disturbing as it does suggest a more aggressive mainland response, which triggered a wave of risk aversion across global markets."
Hong Kong fell 1.5% in the morning session while Shanghai shed 0.7% by lunch.
Tokyo retreated more than one percent by the break as exporters were hit by a rush into the safe-haven yen, Sydney fell 0.3%, Seoul dropped 0.7% and Singapore dived 0.8%.
There were also losses in Manila, Jakarta, Taipei and Wellington.
Emerging market currencies recovered Monday's losses that came on the back of the shock win in an Argentina presidential primary election by populist centre-left candidate Alberto Fernandez over incumbent Mauricio Macri.
The news saw the country's peso dive 30% at one point and the stock market lost more than a third of its value.
OANDA Asia-Pacific senior market analyst Jeffrey Halley said that while contagion from Argentina would be limited, "what it does highlight is that economic populism is alive and well in all corners of the globe - a far more worrying development in the long-term than a US-China trade war."
Hong Kong - Hang Seng: DOWN 1.5% at 25 434.92
Tokyo - Nikkei 225: DOWN 1.2% at 20 440.51 (break)
Shanghai - Composite: DOWN 0.7% at 2 794.07 (break)
Euro/dollar: DOWN at $1.1183 from $1.1217 at 2050 GMT
Pound/dollar: DOWN at $1.2060 from $1.2076
Euro/pound: DOWN at 92.70 pence from 92.84 pence
Dollar/yen: UP at 105.46 yen from 105.28 yen
West Texas Intermediate: DOWN 12 cents at $54.81 per barrel
Brent North Sea crude: DOWN 18 cents at $58.39 per barrel
New York - Dow: DOWN 1.5% at 25 896.44 (close)
London - FTSE 100: DOWN 0.4% at 7 226.72 (close)