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09 May 2004

Arapax and Zyban
I have just weaned myself of Arapax a week ago, was taking 10 mg every 4 days for the last two weeks. Reason for doing it was due to the fact that I want to start going on Zyban in order to stop smoking and don't want to take both at the same time. Would it be save to start immediately with the Zyban or should I wait a couple more weeks before taking it? Do not want to do anything dangerous or unhealthy.
Answer 878 views

01 Jan 0001

Goodmorning, an,
As the marketers of Zyban have neglected to ever contact me or provide me with any information about the product, I do not use it or at this stage, recommend it ; and thus I don't know what specific precautions they might be recommending here in SA. However, here is some basic information about Zyban precautions, and interactions, from a pharmacy source :
" Precautions to Consider Before Taking Zyban
Before taking bupropion tell your doctor if you have a history of seizures, head injury, brain tumor; heart, liver or kidney disease, an eating disorder or any mental conditions, diabetes or if you have any allergies. Limit or avoid consumption of alcoholic beverages; alcohol can increase your risk of seizures. Chronic alcohol users who suddenly stop the intake of alcohol while taking bupropion may increase the risk of having seizures. Suddenly stopping certain tranquilizers (e.g., diazepam, chlordiazepoxide) is not recommended because doing so may increase the risk of having seizures. Elderly patients may be more sensitive to the effects of this drug.
Tell your doctor if you are pregnant or plan to become pregnant before taking this drug. This drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using Zyban is not recommended. Consult your doctor before breast-feeding.
You should not take Zyban if you:
- are taking Wellbutrin (bupropion HCl) Tablets or Wellbutrin SR (bupropion HCl) Sustained-Release Tablets.
- are taking any other medicines that contain bupropion HCl.
- have or have had a seizure disorder (for example, epilepsy).
- have or have had an eating disorder.
- are currently taking or have recently taken a monoamine oxidase inhibitor (MAOI).
- are allergic to bupropion HCl.
(( Aropax is not mentioned, is NOT buproprion nor an MAOI drug mentioned ))
Side Effects of Zyban
Zyban is generally well tolerated. Dry mouth, headache, increased sweating, constipation, anxiety and fatigue may occur. If these effects persist or worsen, notify your doctor.
There is an increased risk of developing a seizure when taking Zyban, although this risk is quite small. Nonetheless, it is important to let us know on your medical history/personal profile about any other prescription or over-the-counter medications that you are taking.
Interacting Zyban With Other Drugs
Zyban and nicotine patches can be used at the same time but should only be used together under the supervision of your healthcare professional. Using Zyban and nicotine patches together may raise your blood pressure. Your healthcare professional will probably want to check your blood pressure regularly to make sure that it stays within acceptable levels.
Do Not Smoke At Any Time if you are using the nicotine patch or any other nicotine product along with Zyban. It is possible to get too much nicotine and experience serious side effects.
It is best not to drink alcohol at all, or to drink very little, while taking Zyban. People who drink a lot of alcohol
and then suddenly stop drinking, may increase their risk of developing a seizure.
Try to avoid drinking any beverages that contain caffeine in the late afternoon or evening. This includes coffee, tea, and many sodas. "
Thus, I don't see any precaution listed specifically referring to Aropax, but take note of the comments about smoking, patches, alcohol, etc.
And remember, folks --- NEVER accept ANY prescription for any new drug from your doctor without insisting that he/she give you a full and detailed description of side-effects, precautions, interactions, etc ; and to be safe, also ask your pharmacist when collecting the prescription, for further information. They are paid to give you that information.

The information provided does not constitute a diagnosis of your condition. You should consult a medical practitioner or other appropriate health care professional for a physical examination, diagnosis and formal advice. Health24 and the expert accept no responsibility or liability for any damage or personal harm you may suffer resulting from making use of this content.
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