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24 Feb 2009

Anti-depressant Side Effects
Hi Doc

I' ve been on Nuzak and Buspar for about 5 years. The dosage used to be very high in the begining - 3xNuzak and 2x Buspar daily, however I' ve been on one a day of each for most of the time. The meds worked very well. However due to the effect on libido my GP prescribed Wellbutrin SR (150)about a month ago. Made me very dizzy - don' t know how to explain it -felt weird -' asof ek sterretjies gesien het'  Didn' t feel depressed though, just a bit emotional (cried easily for silly reasons). Also felt more anxious.

Two weeks into the treatment I went to see a psychiatrist. She said the dizzyness could be withdrawal from the Nuzak and increased the dosage to Wellbutrin XL (300) . Said that I should be a bit more patient.

It' s been a week now. The dizziness seems better (although not completely gone). Just get very anxious very easily - heart pounds fast and I get this ' benoude'  feeling on my chest every now an then. Could this be the Wellbutrin and if so is it dangerous or will get better with time? Im still on the Buspar (one a day) - perhaps this could be increased?

Anyone else experienced these symptoms on Wellbutrin?

Answer 426 views

01 Jan 0001

Pleased to hear you found the meds helped you. There's some reason to think that combining Buspar / Buspirone with an Ad like Nuzak might increase its effectiveness. Wellbutrin is a powerful AD, and has the advantage that it doesn't have the major impact on libido and sex drive which most of the others can have ( though usually not in everyone ). But it might, especially at first, be experienced as a bit stimulating and make one feel a bit odd.
I think the Wellbutrin XL is supposed to be a slow-release version, designed to release the drug gradually all day, rather than dissolving all at once so as to be absorbed rather rapidly --- it may smooth out the blood levels and reduce some of the symptoms. Wellbutrin is relatively newly available in SA, but has been around overseas for many years, and these effects while annoying, don't seem to be dangerous.
The Buspar is primarily to hepp control anxiety symptoms, so ask your psychiatrist ( who may not have realized you were still taking it ) if a slightly higher dose of it might help control the anxiety symptoms you have been experiencing.
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