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13 Dec 2005

I read somewhere that the cause and functional changes of bipolar disorder have not been determined and that no objective biological markers exist that correspond definitely with the disease state. Is this true? Have any genes ever been definitely identified for bipolar disorder?
Answer 369 views

01 Jan 0001

Specific genes haven't been mapped out in detail yet ; but there is strong evidence of genetic influences, which were clear long befopre DNA testing and gene mapping was even thought of, as there have been long-standing studies of the incidence of bipolar disorder in people who have various relatives also affected by the disorder. Some aspects of the chemical imbalances are understood, and more can be inferred from the chemical effects of the drugs that have proved in practice to be useful in controlling aspects of the disorder. But there is no blood test to identify or confirm the diagnosis--- because the chemical anomalies are among the chemicals present in minute quantities within brain tissue, rather than in large quantities in the circulating blood
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