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26 Oct 2006

Eye colour dominance
Good day,

Could you please advise whether Green eye colour is dominant over blue. If so what is the chance (percentage wise) for a child to be born with blue eyes if both parents have green eyes.

Thank you
Answer 384 views
Expert
Geneticist
geneticist

01 Jan 0001

Dear Jo

The situation is quite complex as explained below.
Regards, Maritha

Geneticists have designed a model using the bey 2 and gey gene pairs that explains the inheritance of blue, green and brown eyes. In this model the bey 2 gene has a brown and a blue allele. The brown allele is always dominant over the blue allele so even if a person is heterozygous (one brown and one blue allele) for the bey 2 gene on chromosome 15 the brown allele will be expressed. The gey gene also has two alleles, one green and one blue. The green allele is dominant to the blue allele on either chromosome but is recessive to the brown allele on chromosome 15. This means that there is a dominance order among the two gene pairs. If a person has a brown allele on chromosome 15 and all other alleles are blue or green the person will have brown eyes. If there is a green allele on chromosome 19 and the rest of the alleles are blue, eye color will be green. Blue eyes will occur only if all four alleles are for blue eyes. This model explains the inheritance of blue, brown and green eyes but cannot account for gray, hazel or multiple shades of brown, blue, green and gray eyes. It cannot explain how two blue-eyed parents can produce a brown-eyed child or how eye color can change over time. This suggests that there are other genes, yet to be discovered, that determine eye color or that modify the expression of the known eye color genes.
SOURCE: Human Eye Color Genes by Athro Ltd.: http://www.athro.com/evo/gen/genefr2.html
Eye Color by OMIM, Online Mendelian Inheritance in Man: http://www3.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?227240
The information provided does not constitute a diagnosis of your condition. You should consult a medical practitioner or other appropriate health care professional for a physical examination, diagnosis and formal advice. Health24 and the expert accept no responsibility or liability for any damage or personal harm you may suffer resulting from making use of this content.
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