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08 Feb 2006

Side effects of Concor
Can you please tell me the side effects and implications of taking Concor 5mg daily (beta blocker). My doctor has presicribed them for irregular heart beat.
Can I still have an occasionaly drink whilst on this medication.
Answer 89,451 views
Expert
Pharmacist
pharmacist

01 Jan 0001

Although side effects are not common, the following have been mentioned in the product's package isert:

Lassitude, dizziness, mild headache, perspiration, bradycardia, sleep disorders, restlessness, cold extremities, nausea, vomiting, diarrhoea and skin rash. Constipation, hypotension, paradoxical hypertension, depression, mass gain, paraesthesia, transient hearing loss, heart block, hallucinations, disturbances of vision, blood disorders, fluid retention, muscle cramps, allergic reactions, metabolic disturbances, alopecia, myopathies and stomatitis may occur. Overt psychosis has been reported with other beta-blockers.
Exacerbation of peripheral vascular disease, or the development of Raynaud's phenomenon (due to the unopposed arteriolar alpha-sympathetic activation), hypoglycaemia, skeletal muscle weakness and gastro-intestinal disturbances may occur during treatment with beta-blockers. Severe peripheral vascular disease and even peripheral gangrene may be precipitated.
Special precautions:
Abrupt discontinuation of therapy may cause exacerbation of angina pectoris in patients suffering from ischaemic heart disease. Discontinuation of therapy should be gradual, and patients should be advised to limit the extent of their physical activity during the period in which the medicine is being discontinued.
Bronchoconstriction may occur in patients suffering from asthma, bronchitis and other chronic pulmonary diseases. Since bisoprolol is a highly selective beta1-adrenoceptor blocking agent, it may be used with caution in patients with chronic obstructive airway disease. However, in some asthmatic patients, an increase in airway resistance may occur. This bronchospasm can usually be reversed by commonly-used bronchodilators. Congestive cardiac failure and marked bradycardia may occur.
Bisoprolol may mask the symptoms of hyperthyroidism.
It should be used with caution in patients with hypoglycaemia.

In general alcohol should be take in moderation if at all - In general alcohol may interact with cardioselective beta-blockers and may cause a dangerous drop in BP.
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