Allergy

Real aspirin allergy not that common

Many patients with cardiovascular disease are treated with aspirin because it is effective, low-cost and has few side effects.

Some patients who have a reaction to aspirin are told they are allergic without being tested by an allergist, and stop an otherwise effective therapy.

Hypersensitivity

According to a study presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, 34 percent of patients studied were mistakenly labelled as having aspirin hypersensitivity if they had a history of any gastrointestinal symptoms.

Read: Daily aspirin not for all

The study authors reviewed 5,052 medical records and found aspirin hypersensitivity in only 2.5 percent (131) of the patients.

Hypersensitivity is an exaggerated immune response by the body to an agent – but is not the same as a diagnosed allergy.

"Our study showed none of the patients that were determined to have aspirin hypersensitivity were referred to an allergist for testing to determine if they had a true allergy," said Gabriela Orgeron, MD, lead author.

Read: Does aspirin cut deaths?

"In addition, we found that patients with GI symptoms were mislabeled as having aspirin allergy, which likely deprived them of being treated with aspirin in the future."

How to manage symptoms

While one patient in the study had a severe allergic reaction (anaphylaxis) and one patient had respiratory symptoms, skin reactions were the most commonly documented reaction – found in 19 percent of the patients.

In 39 percent of the cases there was not proper documentation of the type of reaction that occurred.

Read: Aspirin not always good

"It's very important that, similar to penicillin, anyone thought to have an aspirin allergy be referred to an allergist for testing," said allergist and study author Sudhir Sekhsaria, MD, ACAAI fellow. "In cases such as those shown in the study, patients are frequently told to discontinue aspirin therapy or are switched to another medication when there is no reason to do so.

"Allergists can help identify true allergies, and if they are present, help patients find the right course of therapy. If there is not a true allergy, they can help explore how to manage symptoms."

Read more: 

Benefits of aspirin questioned  

Aspirin good for colon 

Aspirin to treat cancer?

We live in a world where facts and fiction get blurred
In times of uncertainty you need journalism you can trust. For only R75 per month, you have access to a world of in-depth analyses, investigative journalism, top opinions and a range of features. Journalism strengthens democracy. Invest in the future today.
Subscribe to News24
Voting Booth
Have you entered our Health of the Nation survey?
Please select an option Oops! Something went wrong, please try again later.
Results
Yes
29% - 9754 votes
No
71% - 24031 votes
Vote