Covid-19 vaccine trials: High rate of side effects reported with placebos - researchers

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A new study has found that the rate of side effects among members of placebo groups in Covid-19 vaccine trials was substantial.

Participants in placebo arms of trials are given a non-pharmacological treatment, such as a sugar pill, or injected with saline solution. Feeling one's physical or mental health improving or experiencing side effects under these circumstances is known as the placebo effect.

The study, published in JAMA Network Open, assessed adverse events (AE) in Covid-19 trials in people in the placebo groups.

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