New Covid-19 study explains how breakthrough infections happen in vaccinated people

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New research established that breakthrough Covid-19 infections were linked to strong tissue compartmentalisation and were only detectable in saliva in some cases. The study indicated that vaccination shortened the duration of high transmission potential and also minimised symptom duration.

The preprint study published in MedRxiv, a journal preprint server, assessed Covid-19 infection in partially and newly vaccinated people.

The researchers enrolled 23 people infected with Covid-19 at various stages of vaccination. Six people were fully vaccinated, six had received their first dose at least two weeks before enrolment, and 11 newly vaccinated people enrolled fewer than 14 days after their first vaccine dose. The participants were vaccinated with the Pfizer, Moderna or Johnson & Johnson vaccines.

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