A drink a day may raise the risk of liver cirrhosis


Daily drinking increases the risk of alcohol-related liver cirrhosis, a new study found.

It's generally believed that overall alcohol consumption is the major contributor to cirrhosis. But these new findings suggest that how often you pour yourself a cocktail or beer - as well as recent drinking - plays a significant role, the researchers said.

Cirrhosis, scarring of the liver, is the final phase of alcoholic liver disease, according to the U.S. National Library of Medicine.

In men, drinking every day raised the risk for cirrhosis more than less frequent drinking. And recent drinking, not lifetime alcohol consumption, was the strongest predictor of alcohol-related cirrhosis, the researchers reported online Jan. 26 in the Journal of Hepatology.

Read: Liver disease up 25% in the UK

"For the first time, our study points to a risk difference between drinking daily and drinking five or six days a week in the general male population, since earlier studies were conducted on alcohol misusers and patients referred for liver disease and compared daily drinking to 'binge pattern' or 'episodic' drinking," said lead investigator Dr. Gro Askgaard, of the National Institute of Public Health, University of Southern Denmark.

"Since the details of alcohol-induced liver injury are unknown, we can only speculate that the reason may be that daily alcohol exposure worsens liver damage or inhibits liver regeneration," Askgaard added in a journal news release.

For the study, researchers looked at data on nearly 56,000 people, aged 50 to 64, in Denmark. Participants filled out food frequency questionnaires and answered questions about their lifestyle habits, including how much beer, wine or hard liquor they drank each week. They were also asked to recall how much they drank, on average, in their 20's, 30's, 40's, and 50's.

Of the total, 257 men and 85 women developed cirrhosis, the researchers found.

Up to a moderate level of weekly consumption, wine appeared to be associated with a lower risk than beer and liquor, the researchers said.

The same general trends were found in women, but no firm conclusions could be reached due to a lack of statistical significance, the study authors said.

Read: How alcohol damages your liver

"This is a timely contribution about one of the most important, if not the most important risk factor for liver cirrhosis globally, because our overall knowledge about drinking patterns and liver cirrhosis is sparse and in part contradictory," said Jurgen Rehm, director of social and epidemiological research at the Centre for Addiction and Mental Health in Toronto.

Rehm, who was not involved with the study, said the report "not only increases our knowledge, but also raises questions for future research." However, "the question of binge drinking patterns and mortality is far from solved," he added, saying there may be genetic differences or other factors not yet discovered that also play a role.

Read more:
Coffee may protect against liver cirrhosis
How alcohol damages your liver
Paracetamol may damage your liver

We live in a world where facts and fiction get blurred
In times of uncertainty you need journalism you can trust. For 14 free days, you can have access to a world of in-depth analyses, investigative journalism, top opinions and a range of features. Journalism strengthens democracy. Invest in the future today. Thereafter you will be billed R75 per month. You can cancel anytime and if you cancel within 14 days you won't be billed. 
Subscribe to News24
Voting Booth
The ANC's leadership race is heating up. Who do you think will be elected party president at Nasrec in December?
Please select an option Oops! Something went wrong, please try again later.
Nkosazana Dlamini-Zuma has got it in the bag
7% - 398 votes
I foresee a second term for Cyril Ramaphosa
82% - 4812 votes
Don’t discount a Zweli Mkhize win
11% - 666 votes
Rand - Dollar
Rand - Pound
Rand - Euro
Rand - Aus dollar
Rand - Yen
Brent Crude
Top 40
All Share
Resource 10
Industrial 25
Financial 15
All JSE data delayed by at least 15 minutes Iress logo
Editorial feedback and complaints

Contact the public editor with feedback for our journalists, complaints, queries or suggestions about articles on News24.