Causes of chronic renal failure

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The aetiology of CKD cannot always be easily determined and it is important to take a detailed history combined with a thorough clinical examination. It is often necessary to include examination of both structure (renal ultrasound) and function (estimated GFR (eGFR)) of the kidneys in the evaluation. CKD often presents as a urinary abnormality in the face of normal renal function that CKD is usually asymptomatic, this concept becomes very important in alerting the doctor that his/her patient has a serious kidney disorder that needs correct diagnosis and management.

Reviewed and revised by Professor A M Meyers, MBBCh, FCP (SA), Cert Nephrology (SA), FRCP (London), Donald Gordon Medical Centre, Klerksdorp Hospital, and National Kidney Foundation of South Africa, March 2015.

Originally written by Dr K. Coetzee, reviewed by Dr R. Moosa, Tygerberg Academic Hospital

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