Cannabis may ease MS symptoms

Use of cannabis extract helps ease painful muscle stiffness among patients with multiple sclerosis (MS), according to a large trial published in the Journal of Neurology, Neurosurgery and Psychiatry.

The "Phase III" test - the final stage in a process to vet a new drug or medical process - took place among 22 centres in Britain.

Over 12 weeks, 144 patients were given daily tablets of tetrahydrocannabinol, which is the active ingredient in cannabis, and 135 were given a dummy pill, also called a placebo.

Doses were gradually escalated, from 2.5 milligrams to a maximum of 25 mg for two weeks, following top-up doses for the remaining two weeks. At the end of the study, 29.4% of people in the cannabis group said they had experienced relief from muscle spasms, compared to 15.7% in the placebo group, according to an 11-point rating.

Improvement in sleep quality

They also reported improvement in sleep quality. Side effects were nervous system disorders and gut problems, but none was severe. MS, a disease that affects the brain and spinal cord, occurs when the immune system attacks the fatty myelin sheaths that insulate nerve cells.

Painful stiffness in the muscles occurs among up to 90% of patients at some time, often leading to poor sleep and impaired mobility.

The trial, led by John Peter Zajicek of Britain's Clinical Neurology Research Group, says standardised doses of cannabis extract can be useful in easing pain and spasms in this disease.

Previous Phase III trials on cannabis and MS have thrown up conflicting results, partly because of the scale by which users report any change in their symptoms, the MUSEC researchers said.

(AFP, October 2012)

Read more: 

Marijuana use may increase risk of testicular cancer

Cure muscle pain with ginger

Researchers halt multiple sclerosis in mice


We live in a world where facts and fiction get blurred
In times of uncertainty you need journalism you can trust. For 14 free days, you can have access to a world of in-depth analyses, investigative journalism, top opinions and a range of features. Journalism strengthens democracy. Invest in the future today. Thereafter you will be billed R75 per month. You can cancel anytime and if you cancel within 14 days you won't be billed. 
Subscribe to News24
Editorial feedback and complaints

Contact the public editor with feedback for our journalists, complaints, queries or suggestions about articles on News24.