Five people died and another person sustained moderate injuries in a head-on collision on Birch Road in Benoni on Tuesday evening.
According to ER24 spokesperson Ineke van Huyssteen, paramedics arrived on the scene shortly after 20:00 and found one vehicle with five people trapped inside.
"Unfortunately, all five of the occupants showed no signs of life and they were declared dead at the scene by paramedics," Van Huyssteen said.
"The driver of the second vehicle was found lying next to his vehicle standing off the roadway. Upon further assessment, it was found that the man had sustained moderate injuries. ER24 treated the man at the scene before transporting him to hospital for further medical care."
Van Huyssteen said the exact circumstances surrounding the incident were not known to paramedics, but police were on the scene for further investigations.