The mother of newly born twins and two others were arrested in Gqeberha on Thursday for alleged human trafficking.
The authorities were alerted after the woman reportedly looked for a buyer for her five-day-old twin girls.
Hawks spokesperson Yolisa Mgolodela said a joint team of law enforcement officers followed up on leads which led them to a house in Uitenhage where the alleged prospective buyer was arrested and babies rescued.
"Another arrest was affected on the mother of the twins and another suspect, which brought the number of arrestees to three. The twins were admitted to hospital for medical attention as they were dehydrated and severely malnourished. They will be taken to a place of safety upon discharge," she added.
According to information, the prospective buyer was expected to pay R50 per day to the twins' mother to satisfy her drug addiction.
It was also reported the alleged buyer was going to apply for a child grant and give a portion to her on a monthly basis.
Mgolodela said the suspects would appear in the Uitenhage Magistrate's Court on Monday.