Corbisiero arrived in Brisbane on Saturday from England's tour of Argentina and will start in a team with fellow tour replacement Ryan Grant named on the bench. Scotland fullback Stuart Hogg will be the flyhalf.
Props Cian Healy (left ankle ligaments) and Gethin Jenkins (calf muscle) are due to fly out of Australia on Sunday due to their injuries.
The Lions, led by regular captain Sam Warburton, received the toughest test of their tour in a 22-12 win over the Reds on Saturday. The first of three Tests against Australia is June 22 in Brisbane.
Combined Queensland and NSW Country:
British and Irish Lions:
15 Sean Maitland; 14 Alex Cuthbert, 13 Brian O'Driscoll (captain), 12 Jamie Roberts, 11 George North; 10 Stuart Hogg, 9 Conor Murray; 8 James Heaslip, 7 Justin Tipuric, 6 Sean O'Brien; 5 Ian Evans, 4 Richie Gray; 3 Dan Cole, 2 Richard Hibbard, 1 Alex Corbisiero.
Replacements: 16 Rory Best, 17 Ryan Grant, 18 Matt Stevens, 19 Alun Wyn Jones, 20 Toby Faletau, 21 Mike Phillips, 22 Jonathan Davies, 23 Leigh Halfpenny