Harry Kane scored his 200th goal for Tottenham Hotspur on Thursday as he helped fire Spurs to a 3-1 Europa League win at Ludogorets, while 10-man Benfica came back from two goals down to snatch a last-gasp 3-3 draw with Rangers.
England captain Kane opened the scoring for Jose Mourinho's side with just 12 minutes on the clock when he headed home Lucas Moura's corner to bring up his double century of Tottenham goals in his 300th match for the club.
Kane then turned provider for Moura in the 32nd minute when he flashed a perfect low cross for the Brazilian to tap home before being substituted at half-time.
Claudiu Keseru pulled one back for the Bulgarians five minutes after the break but Giovani Lo Celso made sure of the win to draw Spurs level on six points with Group J leaders Royal Antwerp ahead of their match with LASK later on Thursday.
Rangers were poised to make it three wins from three in Group D thanks to an Diogo Goncalves own goal and further strikes from Glen Kamara and Alfredo Morelos which put Steven Gerrard's side 3-1 ahead.
But despite losing Nicolas Otamendi to a straight red card with less than 20 minutes gone, two-time European champions Benfica fought back and in added time levelled when Darwin Nunez raced through and slotted home past Allan McGregor.
The pair are joined on seven points at the top of the group, four ahead of Lech Poznon who beat bottom side Standard Liege 3-1 to leave the Belgians pointless.
Qarabag lost 2-0 at Sivasspor to remain rooted to the bottom of Group I a day after their media manager was suspended by UEFA for reportedly calling for the killing of "all the Armenians, old and young, without distinction".
The social media post in question came amid the conflict between Azerbaijan and Armenia in Nagorno-Karabakh, where Qarabag were founded and based until Armenia's takeover of the region in 1993, forcing the club to relocate to Baku.
Roma took control of Group A with a thumping 5-0 win over Cluj that put them three points clear of the Romanians ahead of the later match between Young Boys and CSKA Sofia.
Paulo Fonseca's side are top on seven points after a powerful display from a second string line that started without Edin Dzeko, Pedro and Chris Smalling which did for a Cluj side shocked by coach Dan Petrescu's decision that the match would be his last in charge.
Henrikh Mkhitaryan gave the Serie A side the lead just 57 seconds after kick off, and Ibanez, a brace from Borja Mayoral - his first goals since signing on loan from Real Madrid - and another strike from Pedro sealed the points.
Fellow Italians Napoli also won, 2-1 at HNK Rijeka, to move level on six points with Group F leaders AZ Alkmaar and Real Sociedad.
La Liga leaders Sociedad are also on six points after beating Alkmaar 1-0, leaving the group on a knife edge with three matches remaining.
In Group E, PAOK Thessaloniki boosted their chances of qualifying for the knockout rounds by thumping PSV Eindhoven 4-1, while Granada are top following their 2-0 win over Cyprus' Omonoia.
Europa League results on Thursday:
Roma (ITA) 5 (Mkhitaryan 2, Ibanez 24, Mayoral 34, 84, Pedro 89) CFR Cluj (ROM) 0
Young Boys (SUI) 3 (Mambimbi 2, 32, Sulejmani 18) CSKA Sofia (BUL) 0
Rapid Vienna (AUT) 4 (Ljubicic 22, Arase 79, Hofmann 87, Demir 90+1) Dundalk (IRL) 3 (Hoban 7, McMillian 81, 90+6-pen)
Arsenal (ENG) 4 (Haugen 45+1-og, Sinyan 62-og, Pepe 69, Willock 88) Molde (NOR) 1 (Ellingsen 21)
Slavia Prague (CZE) 3 (Kuchta 16, 71, Sima 43) Nice (FRA) 2 (Gouiri 33, Ndoye 90+3)
Hapoel Beer-Sheva (ISR) 2 (Acolatse 11, 25) Bayer Leverkusen (GER) 4 (Bailey 5, 75, Dadya 39-og, Wirtz 88)
Benfica (POR) 3 (Goldson 2-og, Silva 77, Nunez 90+1) Rangers (SCO) 3 (Goncalves 24-og, Kamara 35, Morelos 51)
Lech Poznan (POL) 3 (Skoras 14, Ishak 22, 48) Standard Liege (BEL) 1 (Lestienne 29)
PAOK (GRE) 4 (Schwab 47, Zivkovic 56, 66, Tzolis 58) PSV Eindhoven (NED) 1 (Zahavi 21-pen)
Omonoia Nicosia (CYP) 0 Granada (ESP) 2 (Herrera 4, Suarez Charris 64)
Real Sociedad (ESP) 1 (Portu 58) AZ Alkmaar (NED) 0
Rijeka (CRO) 1 (Muric 13) Napoli (ITA) 2 (Demme 43, Braut 62-og)
Zorya Luhansk (UKR) 1 (Kochergin 81) AEK Athens (GRE) 4 (Tankovic 7, Mantalos 34, Livaja 54, 81)
Leicester City (ENG) 4 (Iheanacho 21, 48, Praet 67, Maddison 78) Braga (POR) 0
AC Milan (ITA) 0 Lille (FRA) 3 (Yazici 22-pen, 55, 58)
Celtic (SCO) 1 (Griffiths 65) Slavia Prague (CZE) 4 (Julis 26, 45, 77, Krejci 90)
Villarreal (ESP) 4 (Bacca 4, 52, Alex Baena 71, Nino 81) Maccabi Tel-Aviv (ISR) 0
Sivasspor (TUR) 2 (Osmanpasa 11, Kayode 88) Qarabag (AZE) 0
Ludogorets (BUL) 1 (Keseru 50) Tottenham (ENG) 3 (Kane 13, Lucas 33, Lo Celso 62)
Antwerp (BEL) 0 LASK Linz (AUT) 1 (Eggestein 55)
Feyenoord (NED) 3 (Haps 63, Kokcu 71, Geertruida 72) CSKA Moscow (RUS) 1 (Senesi 80-og)
Dinamo Zagreb (CRO) 1 (Atiemwen 76) Wolfsberg (AUT) 0
Red Star Belgrade (SRB) 2 (Kanga 12 Katai 59) Gent (BEL) 1 (Odjidja-Ofoe 31)
Hoffenheim (GER) 5 (Dabbur 22, 30 Grillitsch 59, Adamyan 71, 76) Slovan Liberec (CZE) 0