Arsenal subs: Ryan, Bellerin, Gabriel, Willian, Cedric, Nelson, Elneny, Nketiah, Azeez.
Arsenal starting XI: Leno, Chambers, Holding, Mari, Saka, Xhaka, Partey, Ceballos, Pepe, Lacazette, Martinelli.
Sheffield United subs: Foderingham, McBurnie, Mousset, Lowe, Jagielka, Bogle, Brewster, Bryan, Ndiaye.
Sheffield United starting XI: Ramsdale, Baldock, Stevens, Ampadu, Egan, Osborn, Fleck, Lundstram, Norwood, Burke, McGoldrick.
Match officials - Referee: Peter Bankes. Assistants: Neil Davies, James Mainwaring. Fourth official: Lee Mason. VAR: Jarred Gillett. Assistant VAR: Stephen Child.
Eight of Alexandre Lacazette’s 11 PL goals this season have been scored away from home.
Arsenal have failed to keep a clean sheet in their last nine PL matches. Only twice have they had a longer run without a shutout, with 11-match sequences that ended in March 2018 and February 2002 respectively.
A competition-high 15 of Sheff Utd's 24 PL defeats this season have been by a single goal. No side have lost more matches by a one-goal margin in a single campaign.
Sheff Utd are unbeaten in all four of their Premier League home matches against Arsenal (W2 D2), winning their last two 1-0 in 2006/07 and 2019/20.
Hello and welcome to today's live coverage of Sheffield United vs Arsenal in the English Premier League. Kickoff is at 7pm UK time.
We are underway at Bramall Lane!
Close! Arsenal have their first attack and nearly score. Martinelli slips a pass to Saka up the side and his shot rifles fractionally over the bar.
A surprise from Mikel Arteta today as it's Xhaka at left back to cover for the injury of Tierney.
A long pass sees Pepe get in-behind Stevens with his strength but the Ivorian winger takes too long to deliver and loses the ball.
Saka now gets forward down the right in a very influential start by the teenager. He squares a pass into the box and Ampadu has to clear before Martinelli can finish. Strong start by Arsenal.
CHANCE! Sheff Utd have a really good chance as Osborn fires a pass into McGoldrick in the box and he steadies himself before firing just wide of the post with his weaker left foot. Good opening for the hosts.
The home team have had 60% of the ball thus far. Arsenal look quite content to play on transitions and have not pressed the hosts too aggressively.
Ceballos now looks for the ball to the back post. It finds Chambers to volley across the box but no Arsenal player gets onto it.
Partey strikes a shot from long range for Arsenal but Norwood does well to throw himself in front of it. They may be heading to the Championship but the hosts are still fighting for the shirt.
Xhaka puts a long pass down the left for Martinelli's run away from Ampadu but Ramsdale reads the danger really well to clear outside his box.
In typical Ramsdale fashion, he follows up that good goalkeeping with a comic moment. He clears the ball straight into Lacazette on the edge of the big box and has to catch the deflection. A lucky esape.
Side netting! Ceballos backheels to Lacazette who spreads play to Martinelli on the left. The Brazilian goes on the outside and tries a shot from a narrow angle which doesn't test Ramsdale. Somewhat wasteful that from Arsenal's left-sided forward.
Arsenal have a long spell of good possession with Ceballos and Partey heavily involved but as soon as the ball reaches Pepe on the right, he gives it away.
It's been a decent game but without many chances or much creativity. Pepe is the only player on the pitch so far to have made a successful dribble.
Martinelli receives wide left and cuts inside. He is clearly desperate to get the ball onto his right foot and when he does, he draws a save out of Ramsdale albeit a comfortable one.
Now Martinelli gets to the byline and puts a ball across the area. It finds Chambers and he strikes for goal but Sheff Utd block the effort away well. Arsenal are stepping things up here.
GOAL! LACAZETTE! Arsenal take a 1-0 lead. Saka finds Ceballos and he backheels a pass for Lacazette to run onto and sidefoot past Ramsdale. Sheffield United 0-1 Arsenal.
That goal is Lacazette's 12th league goal this season with nine of those coming on the road. That goal was reminiscent of Wenger's Arsenal in their pomp.
Arsenal come close again as Lacazette drops off and slips in Saka but the England international is unable to control the pass and the ball runs through to a grateful Ramsdale.
The last 25 minutes have seen Arsenal having 63% of the ball and all 5 shots in that period. It's been one way traffic after an even opening 10 minutes.
Since the goal, Arsenal have monopolised the ball completely.
Pepe wins a corner off Egan with some strong running. He takes the corner himself, Lacazette flicks on and Martinelli has a shot which McGoldrick blocks well. Close that!
Pepe takes another corner, Sheff United try to break but lose the ball cheaply, Lacazette has a shot blocked and Sheff Utd try to break again but lose the ball. An action-packed sequence that.
McGoldrick runs at Arsenal and wins a first corner. The hosts keep the ball alive and Egan strikes a volley at goal which Leno gets behind and saves well.
HALF TIME. Arsenal lead 1-0 through Lacazette's 33rd minute goal in a dominant display. Join us in 15 minutes for the second half.
1' Pepe takes a corner from the left for Arsenal but it's a poor delivery and Sheffield United clear. VAR looks at a possible penalty for handball but it wasn't deliberate by Norwood.
The fourth official raises his board and it's one minute additional time to be played.
The second half is underway. No changes for either side.
Sheff Utd make a strong start to the half. First, a McGoldrick shot is deflected out for a corner. Then, Egan gets onto Norwood's cross and draws a punched save out of Leno. Much better.
Burke makes a strong run down the left and goes past Chambers but the Arsenal right back shows good recovery pace and makes a good tackle.
Lacezette goes close to making into 2-0 with a curling shot from the edge of the box but it goes over the crossbar. Good approach play from Pepe set that up.
Saka leads a counter for Arsenal after McGoldrick has a shot blocked. Baldock eventually gets back and wins the ball, and a freekick, off Saka.
Pepe and Saka link up very well for Arsenal in a tight space on the right. Pepe eventually fires off a shot which is blocked but the ball goes to Lacazette on the left. He proceeds to deliver a bizarre cross miles behind his teammates.
Martinelli is down injured for Arsenal and seems to have injured his ankle again. He is receiving treatment but may not be able to continue.
Double change for Sheffield United. Off go front pairing Burke and McGoldrick and on come Brewster and McBurnie.
Saka is now down holding his thigh for Arsenal. Martinelli is back on but doesn't look comfortable.
Saka isn't going to be able to continue. Willian takes his place for Arsenal.
GOAL! MARTINELLI! 2-0 to Arsenal. Pepe cuts inside from the right and draws a save out of Ramsdale but he pushes it straight to Martinelli who taps home. Sheff Utd 0-2 Arsenal.
Lacazette does well on the edge of the box to play a one-two with Ceballos and win a freekick off Ampadu. VAR checks that it wasn't inside the box and replays show it was just outside. Freekick in a good position...
Willian takes the freekick but it's straight into the wall. Not a very good attempt. The veteran still awaits his first goal of the season.
Mari is shown a yellow card for Arsenal for a foul on McBurnie.
Pepe puts in a good cross but it has too much space and Martinelli can't quite get onto it.
Sheff Utd make a change as they withdraw sub McBurnie for Mousset. He had taken a knock from Mari but seemed fine to play on - that must be tactical.
Arsenal make a change as Elneny replaces Martinelli.
GOAL! LACAZETTE! 3-0 to Arsenal. Partey receives in midfield and plays a glorious through ball for Lacazette, who finishes with aplomb. Sheffield United 0-3 Arsenal.
Mousset has a chance to pull a goal back but his effort is awful with Brewster free for a pass. That sums up the home team's afternoon.
The fourth official raises his board and indicates four additional minutes at the end of the 90.
Arsenal make their final change as Nketiah replaces Lacazette.
FULL TIME. A comfortable win for Arsenal as Lacazette got a brace and Martinelli got the other in the absence of Aubameyang. Sheffield United 0-3 Arsenal. Thanks for joining us.
4' Ampadu is yellow carded for fouling Nketiah.