The teams are out and we’re moments away from kick-off!
There is also a Chelsea debut for keeper Edouard Mendy. Chilwell makes his first start at left-back, having made his debut off the bench against Barnsley in their third-round win last week.
Debut for Reguilon for Tottenham, as Mourinho makes near-wholesale changes from the draw with Newcastle on Sunday. Only Lloris and Eric Dier keep their places. Dele Alli is once again not in the squad.
Tottenham Starting XI: Lloris, Alderweireld, Dier, Tanganga, Aurier, Gedson, Ndombele, Sissoko, Reguilon, Bergwijn, Lamela
Subs: Hart, Doherty, Sanchez, Davies, Hojbjerg, Lucas, Kane
Chelsea Starting XI: Mendy, Azpilicueta, Zouma, Tomori, Chilwell, Jorginho, Kovacic, Hudson-Odoi, Mount, Werner, Giroud
Subs: Kepa, James, Emerson, Kante, Barkley, Havertz, Abraham
The team news will be out shortly!
Good evening and welcome to our live coverage of this English League Cup clash between Tottenham and Chelsea, live from Tottenham Hotspur Stadium!
Kick-off! Spurs get the match underway!
Chilwell pulls it back to Werner who tries to swing a cross into the area, but it flies out for a goal kick.
Tottenham set up to counter but Lamela and Bergwijn are well blocked off every time they get the ball and try to attack.
75% possession to Chelsea so far; all in the middle of the park though. Tottenham looking tough to break down with the back three.
SHOT! Mount picks up the ball in a similar area 25-yards out and shapes to shoot. He makes good contact with it, but it goes wide.
GOAL! WERNER! Azpilicueta picks out Werner just inside the box, who steadies himself before firing a powerful shot into the bottom corner! Tottenham 0-1 Chelsea!
Injury concern for Totttenham as Eric Dier is down and the physios are on.
Dier looks okay to continue! Sanchez sits back down.
SAVE! Mendy denies Lamela with his right foot after the Argentine had turned and shot in the area. He then gathers the loose ball thereafter.
Lamela nicks the ball off the toe of Kovacic before turning and trying to drive forward, but he is surrounded by blue shirts and Chelsea hustle him off the ball.
Half time! The referee brings an end to the half, with the score at the break: Tottenham 0-1 Chelsea
Yellow card: Kovacic is booked for a foul on Lamela.
There will be a minimum of 2 minutes added time.
Second half! Chelsea get the match restarted! No changes for either side at half time.
SAVE! Good work from Aurier as he drives forward and crosses for Reguilon. He sidefoots it towards goal with power, and Mendy palms it over!
CHANCE! A ball over the top finds Bergwijn. He turns and tries to lay it back to Ndombele on the edge of the area to Aurier who is only ever bending it wide with his left foot.
NO PENALTY! Bergwijn goes down under what seems to be a clumsy challenge from Chilwell, but referee waves any protests away.
Yellow card: Aurier is booked for a late challenge.
Yellow card: Tanganga is booked for a foul on Mount.
Substitution for Spurs: Hojbjerg comes on for Gedson in a tactical switch.
Substitution for Chelsea: Emerson comes on for Chilwell in a tactical switch.
Substitution for Spurs: Kane comes on for Tanganga in a tactical switch.
A nervous moment for Mendy as he comes out to collect a corner and fails to claim it. Spurs get possession and work it left to Reguilon, but the cross is then held by the Chelsea goalkeeper.
Substitution for Chelsea: Kante comes on for Kovacic in a tactical switch.
WIDE! Aurier with a cross into the heart of the Chelsea area. It travels through to Reguilon, but he seems caught in two minds before heading it wide.
CHANCE! Bergwijn's slip allows Kante to find Mount. He squares for Werner in the area, who shifts it out of his feet before forcing Lloris into a save with his low drive.
OVER! Hudson-Odoi cuts in onto his right foot from the edge of the area, but fires over the bar!
Chelsea break two versus one and Mount tries to square for Werner, but he makes it far too obvious and Dier manages to intercept.
OVER! Lamela threads it through for Kane who turns inside Tomori, but then bends it over the bar with his left foot.
Yellow card: Jorginho is booked for a late challenge in the middle of the park.
GOAL! LAMELA! Reguilon plays a good cross up to Lamela at the back post who takes a touch before firing it past Mendy! 1-1!
Will anyone be able to win this before penalties now?
There will be a minimum of 3 minutes added time.
And that's the end of normal time! Into a penalty shootout we go…
FULL TIME: Tottenham qualify for the next round winning 5-4 on penalties following a 1-1 draw after 90 minutes!