Kick-off is at 21:40 (SA time).
Coach Daniel Hourcade named the same XV on Thursday and made only one change to the replacements with utility back Lucas Gonzalez Amorosino taking the place of Ramiro Moyano.
The Pumas led the Springboks by 10 points with 10 minutes left in Nelspruit last Saturday only to concede two tries and lose 30-23 in the opening round.
"We controlled the game for 70 minutes in South Africa before making mistakes that proved costly," said Hourcade.
"There are issues to correct and others that we have to repeat in order to prevent the Springboks playing their game."
The teams have met once before at Estadio Padre Ernesto Martearena in north-western city Salta with a late penalty giving South Africa a 33-31 victory two seasons ago.
15 Joaquín Tuculet, 14 Santiago Cordero, 13 Matías Orlando, 12 Juan Martín Hernández, 11 Manuel Montero, 10 Nicolás Sánchez, 9 Martín Landajo, 8 Facundo Isa, 7 Juan Manuel Leguizamón, 6 Pablo Matera, 5 Tomás Lavanini, 4 Matías Alemanno, 3 Ramiro Herrera, 2 Agustín Creevy (captain), 1 Nahuel Tetaz Chaparro
Substitutes: 16 Julian Montoya, 17 Felipe Arregui, 18 Enrique Pieretto, 19 Guido Petti, 20 Javier Ortega Desio, 21 Tomas Cubelli, 22 Santiago Gonzalez Iglesias, 23 Lucas González Amorosino
15 Johan Goosen, 14 Ruan Combrinck, 13 Lionel Mapoe, 12 Damian de Allende, 11 Bryan Habana, 10 Elton Jantjies, 9 Faf de Klerk, 8 Warren Whiteley, 7 Oupa Mohoje, 6 Francois Louw, 5 Lood de Jager, 4 Eben Etzebeth, 3 Vincent Koch, 2 Adriaan Strauss (captain), 1 Tendai Mtawarira
Substitutes: 16 Bongi Mbonambi, 17 Steven Kitshoff, 18 Lourens Adriaanse, 19 Pieter-Steph du Toit, 20 Jaco Kriel, 21 Rudy Paige, 22 Morne Steyn, 23, Jesse Kriel