The Lions head to Belfast for their final United Rugby Championship tour fixture against Irish side, Ulster, at Kingspan Stadium on Friday.
Prop Carlu Sadie makes a return to the starting line-up, with lock Reinhard Nothnagel and flank Sibusiso Sangweni collecting their first starting berths in the competition.
Nothnagel comes in for the injured Pieter Jansen van Vuren, while Sangweni features in what reflects a few selection rotations in the match-day 23.
Following last week's 13-9 loss to Glasgow Warriors, Lions head coach Ivan van Rooyen is upbeat ahead of his team's fourth round encounter.
"There were quite a few aspects we felt we improved on in our performance against Glasgow Warriors last week, and that's the kind of momentum we want to take into the Ulster game."
"This is the final game of our 4-week tour so naturally we want to end it on a high," he concluded.
Wilhelm van der Sluys, Emmanuel Tshituka and flyhalf Fred Zeilinga will all have an opportunity to make their tournament debuts off the substitutes bench on Friday.
Kicks-off is at 20:35 (SA time) on Friday.
15 Divan Rossouw, 14 Stean Pienaar, 13 Manuel Rass, 12 Burger Odendaal (captain), 11 Rabz Maxwane, 10 EW Viljoen, 9 Andre Warner, 8 Ruhan Straeuli, 7 Vincent Tshituka, 6 Sibusiso Sangweni, 5 Reinhard Nothnagel, 4 Ruben Schoeman, 3 Carlu Sadie, 2 Jaco Visagie, 1 Sti Sithole
Substitutes: 16 PJ Botha, 17 Ruan Dreyer, 18 Asenathi Ntlabakanye, 19 Wilhelm van der Sluys, 20 Emmanuel Tshituka, 21 Morne van den Berg, 22 Fred Zeilinga, 23 Wandisile Simelane