Hello and welcome to our live coverage of the Premier League clash between Brighton and Hove Albion and Manchester United from the Amex Stadium.
Manchester United: De Gea, Darmian, Smalling, Rojo, Young, Fellaini, Pogba, Matic, Mata, Rashford, Martial.
Brighton and Hove Albion: Ryan, Bruno, Dunk, Duffy, Bong, Knockaert, Gross, Stephens, Propper, Izquierdo, Murray.
Manchester United have lost at Newcastle and Huddersfield in the Premier League this season - they've never previously lost away against as many as three promoted sides in a single top-flight campaign before.
Away from home, the Red Devils have won three in a row, last winning four consecutively in April 2017.
Paul Pogba has scored three goals in his last four Premier League games.
Lukaku is out for Manchester United while back-up goalkeeper Sergio Romero has been injured recently.
Eric Bailly is fit to play despite missing out on the last two matchday squads.
Manchester United are second on the log and Brighton and Hove Albion are 14th.
Kick-off! The first half begins.
Rashford is brought down by Duffy and it is a clumsy challenge. United have a free kick just outside the box.
Offside! Fellaini is caught offside as he heads the ball into goal, after the free kick, and that will be disallowed.
United are controlling the ball and play in the opening minutes.
First real attack from Brighton and they probe away with Knockaert putting in a good run. United scramble back to defend and eventually Stephens' shot goes just wide of goal.
This is turning out to be a decent start from Brighton. They have looked to ask questions off the defence. Gross with the latest shot which goes straight to De Gea.
The score remains on 0-0 but it has been an exciting start to the game. United have almost scored through a free kick and Brighton have responded with a positive start.
Brighton win the ball again and they look to build on the left wing.
Brilliant shot on goal! Murray gets some space and just shoots for goal, a slightly long range shot and De Gea does well to dive and palm it away from his goal.
Poga with a long range cross but Brighton are strong in defence. The score remains on 0-0.
Rashford gets the ball after a mistake from Brighton but he takes too long to cross the ball and Brighton defend well.
Chance! Brighton are playing like they want this more. Duffy with the shot and it was on target, De Gea makes a good save again.
Izquierdo runs in from the left wing and shoots, De Gea has to make the save again. The keeper is being kept busy.
United have looked sloppy in the last few minutes and Fellaini gives the ball away and Brighton build from the right, Gross gets in a shot but De Gea blocks it out for a corner.
We are in the final 10 minutes of the first half and Brighton have looked like they want this more. United have been sloppy as the half has gone on.
Mata gets the ball and just loops the ball from outside the box but it goes straight to the keeper.
United are struggling to impose themselves. They give the ball away again and Brighton look to build but Murray is caught offside.
United with a corner and Brighton defend it away for another corner.
Bong is injured and is going off the field. A short delay in play.
Just one minute of added time to this half. Mourinho does not look happy with his team.
HALF-TIME: BRIGHTON 0-0 MANCHESTER UNITED. Paul Pogba has lost the ball 13 times, Rashford has lost it 11 times. Brighton have done well to put pressure on United. It will be an exciting second half if Brighton score early.
The second half begins. Brighton kick us off.
Pogba with a shot early int he second half and Ryan makes a good save. United showing some intent in the second half.
YELLOW! Fellaini is brought down by Murray and the referee books him.
Knockaert runs in and takes a shot at goal from 20 yards and wins a corner.
GOAL, BRIGHTON, GROSS! 1-0: Gross scores and Brighton deserve it. Izquierdo overruns the ball and Gross slots the ball in. Brighton lead.
United have fallen apart since the goal. Bruno is played in on the overlap, cuts inside, looks across the six-yard box and Rojo makes a vital block to clear it away.
Brighton are looking more and more positive after the goal.
YELLOW! Gross brings down Mata and is shown the yellow card for it.
The free kick goes over the bar! Brighton are one goal ahead.
Shaw and Lingard come on for United, with Darmian and Fellaini making way.
We are in the final 20 minutes of the game and Brighton are in the lead. Rashford shoots from a long range and Ryan makes a good save.
Knockaert is down and he looks he is injured. A short delay in play and he looks like he will continue.
Brighton are not settling for the lead and they are looking to attack. United need to score quickly to stay in the game.
Martial gets the ball after Rashford and Mata keep it in play on the right wing, Martial shoots and it goes over the goal.
Murray and Smalling clash as Brighton take a free kick, and the referee awards United a free kick.
Pogba has a shot from a really long range, from 30 yards out and it does not trouble the keeper.
Kayal replaces Gross whose goal is the difference between the two sides. Brighton are just a few minutes away from a historic win.
Izquierdo is replaced by March for the final few minutes, Brighton with their second change.
We are in the final few minutes of the game including stoppage time and Brighton look like they will win this. United are desperately trying to find a goal.
Four minutes of added time to this half.
Brighton looking to run the clock down as Murray is replaced with Ulloa.
FULL-TIME: BRIGHTON 1-0 MANCHESTER UNITED. Brighton have done it. This is only their second win against Manchester United in their history and it is an important win for them. A miserable evening for Mourinho and the visitors. Brighton win by one goal.