Top seed Andrey Rublev set up a double duty quarter-final matchup at the ATP and WTA Washington Open on Friday by ousting US 13th seed Maxime Cressy in the US Open tuneup.
World number eight Rublev defeated Cressy 6-4, 7-6 (10/8) after one hour and 42 minutes in a match postponed from Thursday due to rain.
Next up for Rublev is 99th-ranked US wildcard J.J. Wolf, who beat Danish ninth seed Holger Rune 7-5, 4-6, 6-3 in two hours and 36 minutes in their rain-delayed encounter.
Wimbledon runner-up Nick Kyrgios, hometown hero Frances Tiafoe and American Sebastian Korda - whose matches were halted by Thursday's storms - finished off triumphs Friday and advanced to night quarter-finals.
Rublev broke to 2-1 and held from there to win the first set in 35 minutes without facing a break point.
In the second set, Rublev saved a break point in the second game with a backhand winner and battled into the tie-breaker, where he denied Cressy a set point with his eighth ace and captured the victory on his ninth.
Rublev, who had only nine unforced errors, seeks his fourth title of the season after Marseille, Dubai and Belgrade to match Rafael Nadal and Carlos Alcaraz for the most ATP trophies this year.
World number 28 Rune's back-to-back double faults handed Wolf the first set. The Dane forced a third set only to surrender a break in the penultimate game and fall on a Wolf ace in an eight-minute final game.
Australia's 63rd-ranked Kyrgios broke US fourth seed Reilly Opelka in the first game after their resumption for a 3-1 lead in the second set and went on to complete a 7-6 (7/1), 6-2 victory.
Kyrgios, who won the most recent of his six ATP titles at Washington in 2019, booked a last-eight date with 10th seed Tiafoe, who reached his first hometown quarter-final by eliminating Dutch eighth seed Botic van de Zandschulp 4-6, 6-2, 6-3. Rain had stopped them after two sets.
World number 54 Korda, 22-year-old son of 1998 Australian Open winner Petr Korda, dispatched Bulgarian fifth seed Grigor Dimitrov 4-6, 6-1, 6-2 by romping through the last two sets Friday.
Korda's reward was a quarter-final berth against Sweden's 115th-ranked Mikael Ymer.
Former world number one Victoria Azarenka advanced to the last eight in a postponed women's match, dispatching Czech Tereza Martincova 7-6 (9/7), 6-2.
World number 20 Azarenka, 33, won an 80-minute first set then dominated the second to secure her first WTA quarter-final berth since January in Adelaide.
Azarenka, a two-time Australian Open champion and three-time US Open runner-up, was set for her second match of the day, against Chinese lucky loser Wang Xiyu, for a semi-final spot.
Estonia's Kaia Kanepi defeated Anna Kalinskaya 6-7 (4/7), 6-4, 6-3 to reach the semi-finals.
Kanepi, her age and world rank at 37, seeks her fifth career WTA title but first since the 2013 Brussels Open. Her only hardcourt title came at Brisbane in 2012.
Results from Friday's fifth day of the ATP and WTA Washington Open (x denotes seed; players representing Russia and Belarus are banned from competing under the name or flag of their countries):
Andrey Rublev (x1) bt Maxime Cressy (USA x13) 6-4, 7-6 (10/8)
J.J. Wolf (USA) bt Holger Rune (DEN x9) 7-5, 4-6, 6-3
Frances Tiafoe (USA x10) bt Botic van de Zandschulp (NED x8) 4-6, 6-2, 6-3
Nick Kyrgios (AUS) bt Reilly Opelka (USA x4) 7-6 (7/1), 6-2
Sebastian Korda (USA) bt Grigor Dimitrov (BUL x5) 4-6, 6-1, 6-2
Kaia Kanepi (EST x6) bt Anna Kalinskaya 6-7 (4/7), 6-4, 6-3
Victoria Azarenka (x4) bt Tereza Martincova (CZE) 7-6 (9/7), 6-2